How can we use stem cells to improve human health?
Meet the Bio Builders—a team of scientists in the Thomson Lab at the Morgridge Institute for Research who are using stem cells to repair damaged tissue and improve human health treatments. In the resources below, you’ll learn about these scientists and their lab, discover why their research matters in real life, and try out an activity. Take notes as you explore!
Learn Why Research Matters
The Thomson Lab pioneered stem cell research, and they now use stem cells to repair damaged tissue and improve human health treatments. In the following video, you’ll learn about one reason why they research this, through a real-world story about a woman who was born a twin but lost her sister at a young age from a nervous system disorder.
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Questions to Consider:
Now that you know a little about stem cells from Shannon’s story, what else could you imagine using stem cells for? Why was she fascinated by them?
How did Shannon’s sister, Lauryn, influence Shannon’s career? Is there someone in your life who has had a lot of impact on you?
“With stem cells, we have all this potential to understand things that we haven’t understood, and the potential to cure, or at least have an improved quality of life for patients.”
Meet The Scientists
There are 4 cards to read.
Elizabeth Perrin
Research Specialist
I have many tasks in the lab! Some days I make cells to use in experiments. Other days I’m creating proteins, working with students, or helping to get our blood vessel grafts ready to test!
Jue Zhang
Assistant Scientist
I make tissue-engineered blood vessels! These blood vessels get used to help people who need bypass surgery, which redirects blood around a section of a blocked artery in your heart.
Marcela Tabima
Biomedical Engineer
I work in the Thompson Lab and create replacement blood vessels. These are the tubes that carry blood pumped from the heart to the rest of the body.
Bret Duffin
Research Coordinator
I grow stem cells in the lab. These are cells that can grow into any other type of human cell when given the right conditions. I study how to do this! I get them to grow into other cell types of the body.
Ask questions!
Being a scientist means asking new questions and learning new things. Click through the topics below to ask questions of the scientists at the Thomson Lab and learn about their research.
Click on a tab above to begin.
What is your lab and what do you study there?
What are arteries?
What is a stem cell?
How do you use stem cells to make artery replacements?
How do you make stem cells grow how you want them to?
How do you know your artery replacements will work?
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Do Science!
Science Practices Activity
Now put what you’ve learned into practice! How can you make an artery using stem cells and a scaffold? Join Elizabeth to find out.
Project Credits
Producer
Ryan Hendricks
Coordinating Producer
Mia Forslund
Videography
Ryan Hendricks
Ian Glodich
Video Editor
Ryan Hendricks
Web Design
Charles Barrows
Web Development
John Vieth
Tim Schneider
Graphic and Motion Design
Charles Barrows
Jen Hadley
Steve Dorchester
Brian Lorbiecki
Amanda Roslansky
Video Captioning
Catie Pfeifer
Vicki Way Kipp
University of Wisconsin Cultural Linguistic Services
Science Education Consultant
Wesley Marner II, PhD, Morgridge Institute for Research
Educator Guide and Activities
Mia Forslund
Elizabeth Perrin
Ryan Hendricks
Wesley Marner II, PhD, Morgridge Institute for Research
Jen Hadley
Scientists
Elizabeth Perrin
Marcela Tabima, PhD
Shannon Strader
Bret Duffin
Sarah Webster
Jue Zhang, PhD
Project Partners
Morgridge Institute for
Research
Wisconsin Alumni Research Foundation
Wisconsin Institute for Discovery
James Thomson Lab
Special Thanks To
Girls Inc. of Greater Madison at the Goodman Community Center
Executive Producer
Megan Monday
Director of Education
Alyssa Tsagong
Director of Television
Jon Miskowski
Educator Cohort
Joy Aragones
The Prairie School
Wind Point, WI
Kathy Biernat
Notre Dame School of Milwaukee
Milwaukee, WI
Jessica Buckley
Wedgewood Park Middle School
Milwaukee, WI
Lisa Graf
Merrill Middle School
Oshkosh, WI
Aimee Spahos
Waunakee Intermediate School
Waunakee, WI
Emily Watton
West Allis Central High School
West Allis, WI
Funding Provided By
Timothy William Trout Education Fund
a gift of Monroe and Sandra Trout
Dr. Craig & Mrs. Marilyn January
Focus Fund for Education
Friends of PBS Wisconsin
Single Step Foundation
UW Health