Tags

  • Science
  • Grades 6-8
Scientist working in lab

Optical Microscopy in Medicine Lab

Using Lasers to Research Cancer

The Optical Microscopy in Medicine Lab develops new methods to understand and combat cancer. They use high-tech lasers and high-powered magnification to identify patterns in cancerous cell growth and recommend treatment options.

Why Research Matters

Kat’s Story

Kat’s dad was diagnosed with pancreatic cancer when she was in middle school. Kat shares how she navigated this crisis in her early teenage years and shares her path to advocacy: spreading awareness, supporting research, and preparing to make a difference through her own studies.

Transcript

“Nothing feels better than to actually make a difference in the thing that's so problematic for you”

Questions to consider
  • Kat saw a problem in the world and took clear steps to make a difference. What problems do you see that you think could be solved by science? What steps could you take to start getting involved?
  • Kat wanted to learn as much as she could about cancer. What do you already know about cells and about cancer? What do you want to know about cancer?

Science Practices

Melissa Skala

Students Ask Scientists

Ever wonder what scientists do every day, or what kind of equipment they use in their lab? Join middle schoolers from Medford, Wisconsin and researchers from the Optical Microscopy in Medicine Lab to learn more about what research really looks like!

Questions to consider
  • In the video, researcher Tiffany talks about how her lab takes images and videos of cells to study how they change over time. What things can you think of that change over time that you could document in order to study?
  • In the video, researchers Dan and Amani talk about the importance of looking for patterns in their scientific research. Can you think of places in your life where patterns are really important?
Transcript

“One of the biggest takeaways I've learned from being in science is that we actually don't know that much. So… start trying stuff out! You could be the person to discover [something].”

Patterns in Cancer Cells

Lab researcher Amani has taken images with her microscope to find treatments for cancer. Can you help her identify how cancer cells look different from healthy ones?

Patterns Data Sheet
Patterns Data Sheet
Use this data sheet to record your answers to Amani’s questions!

Relate

Meet The Scientists

Read about the scientists, then flip over the cards to learn more (and discover their secret superpower!) Who do you relate to the most?

There are 4 cards to read.

Melissa Skala
Melissa Skala
Principal Investigator

I am a professor at UW-Madison in Biomedical Engineering. I mentor people in my lab to become independent researchers, set the direction of our research, and communicate our results to the scientific community. 🔬

Amani Gillette
Amani Gillette
Graduate Researcher

I take images with our microscope and run data analysis on them. I’m always trying to answer this question: how do changes to mitochondria (the powerhouse of the cell) impact our microscopes measurements of cells? 🦠

Tiffany Heaster
Tiffany Heaster
Graduate Researcher

I take images of different types of cells found in tumors and create computer programs to understand how each cell type behaves in the tumor. 🖥️

Tongcheng Qian
Tongcheng Qian
Assistant Scientist

I am a stem cell engineer. I generate human tissues with stem cells in the hope of repairing damaged organs. 🧬

Educator Resource

Student using cardboard microscope

Educator Engagement Guide

Optical Microscopy in Medicine Lab

Wondering how to spark additional learning using these media resources? Check out this guide developed by science educators, for science educators.

Inside this guide:

  • Additional information about the lab
  • Additional classroom activities to extend the learning
  • Aligned academic standards (NGSS and WSS)
Download

Project Credits

Producers
Ian Glodich
Jessie Nixon

Videography
Ryan Hendricks
Ian Glodich

Editing
Ian Glodich

Sound
Beauxregard Neylon
Curtis Sorensen

Web
Norman Yuson Cuaño
John Vieth
Tim Schneider

Design
Brian Lorbiecki
Amanda Roslansky
Scott Stetson
Amber Samdahl

Science Education Content
Travis Tangen

Educator Engagement Guide and Activities
Travis Tangen
Christina Swords
Sara Krauskopf
Millie Rolander
Anika Gupta
Kaitlin Edwards
Amani Gilllette

Thanks to our scientists
Melissa Skala
Amani Gillette
Tiffany Heaster
Tongcheng Qian
Daniel Gil

Project Partner
Morgridge Institute for Research
Wisconsin Alumni Research Foundation
Wisconsin Institute for Discovery
Skala Lab

Executive Producer
Megan Monday

Director of Education
Alyssa Tsagong

Director of Television
Jon Miskowski

Educator Advisory Group

Sarah Adumat
Oshkosh Area School District, Oshkosh, WI

Linda Dworschack
North Crawford High School, Soldiers Grove, WI

Jeanine Gelhaus
Medford Area Middle School, Medford, WI

Deborah Hilscher
Traeger Middle School, Oshkosh, WI

Funding Provided By

Timothy William Trout Education Fund
a gift of Monroe and Sandra Trout

Focus Fund for Education

Friends of PBS Wisconsin