Antibiotic Hunters

Superpowered by Students

Have you ever wondered how new antibiotics are discovered?

First, meet Jessi to learn why this kind of research matters in real life today, and then join the Antibiotic Hunters—and students all over the world—to discover new strains of antibiotics, with a goal to improve lives through science. Grab your science notebook to take notes as you go, and then share your discoveries with others!

Learn Why Research Matters

Jessi developed an infection when she was starting high school, but no matter what her doctors did it would not go away. Jessi shares about some of the challenges she faced living with an antibiotic resistant infection, and why it is important to always search for new antibiotics.

View Transcript

Questions to Consider:


Jessi’s experience with antibiotic resistant bacteria made her curious about microbiology, and ultimately inspired her to go into a career in science. What experiences have you had that make you curious about science?


Doctors and scientists often have to try new methods or treatments to find solutions for problems, and it took several tries over many years to find the right solution for Jessi’s infection. Can you think of a time when your first solution didn’t work and you had to try again?

“What I went through in high school was tough, but I’m hoping that it can inspire someone.”

— Jessi Zimmerman

Meet The Scientists

What scientist do you relate to most, and why? Read about the scientists below and flip over the cards to discover their secret superpower. After reading them all, make your own card and tell us about your superpowers!

There are 4 cards to read.

Jo Handelsman
Jo Handelsman
Principal Investigator

I’m the lab leader, which means that I bring the scientists together, attract new people to do training in my lab, and ensure it’s a dynamic and interesting place to work. ✨

Austin Hall
Austin Hall
Graduate Student

As a graduate student, everyday I learn about the world of microbiology. One question I am interested in is: what special tools does a bacteria need to move into a community, also called a microbiome? 🏡

Julia Nepper
Julia Nepper
Postdoctoral Researcher

I study how the microbes in the soil respond to chemicals produced by other organisms living in the soil. 🦠

Amanda Hurley
Amanda Hurley
Postdoctoral Associate

In the laboratory, I spend lots of time testing ideas and generating information from experiments… and then discussing the results with friends. 😊

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What’s your superpower?

Use this fillable PDF template to create your own scientist trading card.


Learn About the Lab

Ever wonder what scientists do every day, or what kinds of phenomena they look for in their lab? Join middle schoolers from Oshkosh, Wisconsin and researchers from the Tiny Earth Network to learn more about what research really looks like!

View Transcript

Questions to Consider


Scientists are always asking questions, and then conducting experiments to try and answer their questions. What questions do you have about the world around you? What kind of experiments could you do to research your questions?


In the video, a researcher named Austin talks about something called a “Zone of Inhibition”. The Zone of Inhibition is an ‘observable phenomenon’—or something that you can see happening. Can you think of any other phenomena that you have observed in nature or in a science experiment?

“It’s important for everyone to pitch in so that we can really see the immense diversity that’s there in soil across the country.”

— Deepa Acharya

Do Science!

Scientist logging notes in notebook
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Science Practices Activity

Lab researcher Amanda is investigating soil samples to hunt for new antibiotics. Can you help her identify soil types that might contain antibiotics?

Project Credits

Ian Glodich
Jessie Nixon

Ian Glodich

Ian Glodich

Beauxregard Neylon
Curtis Sorensen

Norman Yuson Cuaño
John Vieth
Tim Schneider

Brian Lorbiecki
Amanda Roslansky
Scott Stetson
Amber Samdahl

Science Education Consultant
Travis Tangen, WID
Kevin Anderson, PhD, DPI

Educator Guide and Activities
Mia Forslund
Travis Tangen
Christina Swords
Sara Krauskopf
Millie Rolander
Anika Gupta
Kaitlin Edwards
Amanda Hurley

Thanks to our scientists
Jo Handelsman, PhD
Amanda Hurley, PhD
Deepa Acharya, PhD
Marc Chevrette, PhD
Julia Nepper, PhD
Austin Hall
Sarah Miller
Luis Balderrama

Project Partner
Morgridge Institute for Research
Wisconsin Alumni Research Foundation
Wisconsin Institute for Discovery
Handelsman Lab

Executive Producer
Megan Monday

Director of Education
Alyssa Tsagong

Director of Television
Jon Miskowski

Educator Advisors

Sarah Adumat
Oshkosh Area School District, Oshkosh, WI

Traci Marsolek
School District of Eleva-Strum, Strum, WI

Deborah Hilscher
Traeger Middle School, Oshkosh, WI

Funding Provided By

Timothy William Trout Education Fund
a gift of Monroe and Sandra Trout

Focus Fund for Education

Friends of PBS Wisconsin